Which Is Better Microneedling With PRP Or Botox?


First, let us define what is Botox and what is Microneedling with PRP. We must understand that though they treat some similar skin problems and basically both want to make improvements on the patient’s skin, the procedure and how it’s done differ. What would work on a certain skin condition might not work on another.  

What is Botox and how does it work?

Botox is a muscle-weakening or paralyzing medication. It can help cure certain medical problems and reduce skin wrinkles in small doses. Botox is a protein derived from Botulinum toxin, a toxin produced by the bacterium Clostridium botulinum. The toxin that causes botulism is the same. 

Botox is a chemical, but when used properly and in small doses by physicians, it can be beneficial. It may be used for both cosmetic and medicinal purposes.

Botox injections may reduce the presence of wrinkles on the skin as a cosmetic procedure.

The FDA has also recommended it as a cure for a variety of ailments, including eyelid spasms, heavy sweating, certain urinary problems, and migraines.

Botox is a neurotoxin, which means it causes numbness. These chemicals infiltrate the nervous system, interfering with nerve signaling that causes muscle contraction. This is how the drug induces muscle paralysis for a short period of time. 

At the junction where nerve endings touch muscle cells, nerves release a chemical messenger called acetylcholine, which causes every muscle to contract. Acetylcholine binds to receptors on muscle cells, causing them to shorten or contract.

Botox injections block acetylcholine from being released, which prevents muscle cells from contracting. The toxin makes the muscles become less rigid in this way.

What is Microneedling with PRP and how does it work? 

Microneedling with platelet-rich plasma (PRP) is a cosmetic procedure that promotes collagen formation by rolling fine needles over the skin and injecting platelets, which are a component of blood.

Microneedling can be more successful if PRP from the blood is added. Plasma is a liquid of blood, whereas platelets are solid. Platelets aid in the clotting of blood and are also important for the healing of wounds and injuries. Platelet-rich plasma (PRP) is plasma with a greater abundance of platelets than most blood products.

A doctor will take a blood sample and remove the PRP from the rest of the blood using a centrifuge, a rotating instrument.

Proteins, such as growth factors and cytokines, are found in PRP. These proteins aid in the self-repair of skin tissue.

To begin, a practitioner will poke the skin with a micro-needling instrument, creating tiny holes in the skin's surface. They'll then use PRP to stimulate collagen formation and cell replication in these tiny holes.

If people choose to treat such bruises or blemishes on their body or face for aesthetic purposes, they may want to try micro needling with PRP. Acne marks, surgical scars, wrinkles, and fine lines, hyperpigmentation, sun trauma, big pores, and irregular skin texture may all be treated with micro-needling and PRP.

So which procedure is better? 

  • Microneedling with PRP is achieved by using the patient’s own blood, eliminating the chances of infection whereas botox uses botulinum toxin.
  • Though micro-needling with PRP is not cheap, the cost of getting this treatment is way lower than getting Botox.
  • Microneedling with PRP's stimulation of collagen synthesis can have a longer-lasting effect than Botox.
  • Microneedling with PRP has considerably lesser side effects than Botox


Mild Common Side Effects Severe Common Side Effects
Fluid build-up in the tissues of the eyelid, irritated eyes, skin bruising, irritation of the throat, common cold, runny nose, neck pain, urinary tract infection, dry mouth, bronchitis, cough, nausea Muscle weakness, poor eyelid closure, voice change, difficulty in swallowing
Mild Infrequent Side Effects Severe Infrequent Side Effects
Itching and skin rash Infection, double vision, fever 
Mild Rare Side Effects Severe Rare Side Effects
Peripheral neuropathy, dry eye, tinnitus, bloody urine, hair loss, hives, joint and muscle pain, flu-like symptoms, vomiting, diarrhea, intense abdominal pain  Botulism, corneal ulcer, inflammation of the cornea, entropion, hearing loss, abnormal heart rhythm, a reduction in lung function, erythema, seizure, trouble breathing, anaphylaxis, hematoma, 



Mild Side Effects Rare Side Effects
Bruising, inflammation, oozing from the skin, appearance of white papules on the skin, mild flare-up of acne Infection and scarring, herpes simplex, small holes in the skin

Deciding on which is the better treatment still depends on the patient’s condition and overall health and after taking into consideration the pros and cons of both treatments.  

Are you Interested in Learning More About Microneedling with PRP in Gilbert, Arizona?

Atlas Health Medical Group in Gilbert, Arizona specializes in providing Naturopathic / Functional Medicine and microneedling with PRP treatment protocols to the East Valley including Gilbert, Chandler, Mesa, San Tan, and Queen Creek. The benefits of microneedling are quite impressive and occur fairly quickly after treatment. The skin will be somewhat inflamed or pink for around a week, however, it will appear more radiant from the initial skin response. After the swelling subsides, the body will produce more collagen in the affected area for up to six months after the treatment. This will lead to softer, firmer skin, and a reduction in wrinkles, a decrease in acne and acne scarring, a reduction in pore size, a reduction in hyperpigmentation and sun damage, and reduced size and appearance of scars and stretch marks. We pride ourselves on setting the standards of patient care and result-driven treatments so our patients return to health and live the life they intended.  Contact us today for your first appointment!

Atlas Health Medical Group Logo

Ready to Begin Your Journey?

Schedule a free, initial consultation to talk with one of our naturopathic physicians to see if we're a good fit to help you on your journey to health.

Contact Us

Whether you're an existing patient or thinking about working with us, we're happy to hear from you!

Atlas Health Medical Group Logo

1447 W Elliot Rd Suite 103
Gilbert, AZ 85233


Proud Members

Gilbert Chamber Logo