Is Platelet Rich Fibrin (PRF) Therapy Dangerous?


The PRF therapy is a relatively new treatment which has had mixed reviews. It's been said that it can be dangerous because there are no set guidelines for what the patient should expect in terms of pain levels or degree of discomfort they will experience. That being said, many patients have testified to the amazing benefits and desired outcomes they've experienced with this process as evidenced by their testimonials on various social media pages such as Facebook and Twitter where people post about their experiences using Platelet Rich Fibrin (PRF) Therapy injections to heal injuries like tendonitis, shoulder bursitis, rotator cuff injury, tennis elbow and more.

Some say it feels like getting stung by bees when you inject into joints but if you're looking for a relatively painless alternative to surgery, PRP therapy may be just the thing you need.

How Does a PRF Under Eye Treatment Work?

Fibrin is a biological scaffold that forms in the body in response to an injury. Platelets circulating in the blood will bind to a fibrin scaffold. When platelets bind to the fibrin scaffold, they become activated and release growth factors, which initiate wound healing by forming new skin cells, collagen, and blood vessels. Injecting PRF into the face or scalp stimulates new cell growth and collagen production.

How Does PRF Treatment for the Face Treat Under Eye Loose Skin and Dark Circles?

The skin around our eyes is one of the thinnest on our bodies. It is one of the first areas of the body to show signs of aging. PRF is one of the best treatments for this condition, and it may be a better choice than heat-based skin tightening devices and dermal fillers.

PRF facial rejuvenationTM can also improve the results of under-eye fillers. Injecting fillers under the eyes, such as Volbella, can instantly improve hollowness and is a fantastic treatment to instantly rejuvenate this area. However, if fillers are injected too superficially, they can cause puffiness or a bluish tinge under the eyes. Furthermore, fillers are not a good treatment for under the eyes because they cannot treat crepe skin or lines; they can only add volume and lighten some of the dark circles. Typically, the outcomes are negative. By tightening the loose skin under the eyes and improving the dark circles, injecting PRF in addition to the fillers can significantly improve the results of the fillers. We prefer to begin with PRF and then wait for the results before deciding on additional treatments.

How Long Does a PRF Appointment Take?

The most difficult aspect of obtaining PRF under eyeTM treatments is the blood draw and the meticulous production. PRF is very unique, and once produced, we only have 15 minutes to get it into the area before it ceases to be a liquid. Expect a 45-minute appointment time at the office. A full PRF treatment necessitates at least two treatments spaced six weeks apart.


After four to six weeks of treatment, you should see an improvement in skin hydration, texture, and tone. After three to six weeks, new collagen and blood vessels begin to form, and skin repair takes three months. Because cell growth is required to produce new tissue, it takes time to work, but the effects of PRF can sometimes be seen sooner depending on the specific treatment plan and the individual. Because it is a natural process, the results may vary, and changes at the cellular level may not always translate to a visible change.

User:Marine 69-71, CC BY-SA 3.0, via Wikimedia Commons


Do You Need Help Recovering From An Injury With Platelet Rich Fibrin (PRF)?

Atlas Health Medical Group in Gilbert, Arizona specializes in providing Naturopathic / Functional Medicine to the East Valley including Gilbert, Chandler, Mesa, San Tan and Queen Creek. Pain can come from many sources, but when you visit our comprehensive Naturopathic pain management clinic we’ll have a treatment approach tailored to your specific cause of pain as well as addressing contributing factors such as diet, lifestyle and other medical conditions. We are led by top-rated physicians well-versed in treating Athletic injuries using Platelet Rich Fibrin (PRF). We pride ourselves on setting the standards of patient care and result-driven treatments.  Our patients return to health and live the life they intended.  Contact us today for your first appointment!

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